Gene information
Official symbol FCN2
Official full name ficolin 2
Gene type protein-coding gene
Chromosome9q34.3
Alias symbolP35; FCNL; EBP-37; ficolin-2
Gene familyFibrinogen C domain containing; Complement system activation components
Resources
Entrez Gene 2220
HGNC HGNC:3624
Ensembl ENSG00000160339
Vega OTTHUMG00000020892
UCSC uc004cfg.1
GO terms: 36 records
GO Description Category LogP Number of genes Detail
GO:0002221 pattern recognition receptor signaling pathway GO Biological Processes -6.97185167 18 More
GO:0002252 immune effector process GO Biological Processes -24.2648770 43 More
GO:0002253 activation of immune response GO Biological Processes -3.86084748 14 More
GO:0002697 regulation of immune effector process GO Biological Processes -33.2683521 48 More
GO:0002699 positive regulation of immune effector process GO Biological Processes -18.3926498 29 More
GO:0002831 regulation of response to biotic stimulus GO Biological Processes -10.931136 25 More
GO:0002833 positive regulation of response to biotic stimulus GO Biological Processes -5.95822718 13 More
GO:0003823 antigen binding GO Molecular Functions -1.57341070 6 More
GO:0005581 collagen trimer GO Cellular Components -6.28484906 16 More
GO:0006909 phagocytosis GO Biological Processes -7.82039874 17 More
GO:0006910 phagocytosis, recognition GO Biological Processes -1.52968819 4 More
GO:0006956 complement activation GO Biological Processes -7.12107226 12 More
GO:0006959 humoral immune response GO Biological Processes -20.5068158 33 More
GO:0008037 cell recognition GO Biological Processes -2.17557915 8 More
GO:0008228 opsonization GO Biological Processes -7.69370672 5 More
GO:0009617 response to bacterium GO Biological Processes -52.1760880 83 More
GO:0030246 carbohydrate binding GO Molecular Functions -4.83003123 14 More
GO:0030312 external encapsulating structure GO Cellular Components -73.3689453 93 More
GO:0031012 extracellular matrix GO Cellular Components -73.4416071 93 More
GO:0031347 regulation of defense response GO Biological Processes -64.5971043 148 More
GO:0031349 positive regulation of defense response GO Biological Processes -32.1301903 71 More
GO:0032103 positive regulation of response to external stimulus GO Biological Processes -58.7273809 118 More
GO:0042742 defense response to bacterium GO Biological Processes -25.9215771 41 More
GO:0043277 apoptotic cell clearance GO Biological Processes -6.75865733 12 More
GO:0043394 proteoglycan binding GO Molecular Functions -12.1259478 11 More
GO:0045088 regulation of innate immune response GO Biological Processes -6.98001665 16 More
GO:0048306 calcium-dependent protein binding GO Molecular Functions -6.71779738 10 More
GO:0050764 regulation of phagocytosis GO Biological Processes -16.0793009 29 More
GO:0050766 positive regulation of phagocytosis GO Biological Processes -13.5971167 15 More
GO:0050778 positive regulation of immune response GO Biological Processes -17.2528761 40 More
GO:0050829 defense response to Gram-negative bacterium GO Biological Processes -15.0142277 17 More
GO:0050830 defense response to Gram-positive bacterium GO Biological Processes -13.1972375 17 More
GO:0062023 collagen-containing extracellular matrix GO Cellular Components -67.6170082 80 More
GO:0072562 blood microparticle GO Cellular Components -39.0217600 39 More
GO:1905286 serine-type peptidase complex GO Cellular Components -11.3739342 10 More
GO:1905368 peptidase complex GO Cellular Components -4.61293625 9 More
Drug-Gene interaction
view
Related drugs: 1 record
Drug name Interaction type Source PMID View
duloxetine PharmGKB 29407288 view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
ficolin-2 proteomics myocardial infarction[diagnosis] myocardial infarction Vengen IT et al. Sci Rep. 2017
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